Three Guy’s and St Thomas’ clinicians have received Clinical Academic Research Partnership (CARP) awards from the MRC.

The MRC Clinical Academic Research Partnership awards provide support for NHS consultants to increase their research skills and experience. As well as funding for their projects, the awards provide the opportunity to collaborate with researchers from other centres, such as our partners King’s College London, to take forward their research.

Dr Gaia Nebbia

Consultants Dr Gaia Nebbia, Dr Peter Irving and Dr Dan Lumsden have all received awards as part of the scheme.

Dr Gaia Nebbia, a consultant virologist at the Trust, has received funding for a project looking to understand flu in older patients. Her project aims to gather data on older patients’ immune response, particularly their antibodies against influenza. This will help design better vaccines for this age group.

She will work with the latest sequencing methods to diagnose the strain of flu present in older patients. She will then study the fine detail of the antibodies in flu patients and analyse this data alongside information about the flu vaccine patients have received and their outcomes.

Dr Nebbia said: “This is an amazing opportunity and I am looking forward to working with colleagues at King’s, Guy’s and St Thomas’ and Public Health England. I would like to thank Professor Mike Malim, Professor Jonathan Edgeworth and Professor Maria Zambon for their continuous support.”

Dr Peter Irving

Dr Peter Irving is a consultant gastroenterologist. His project is looking at a new treatment for Crohn’s disease using cells from patients’ immune system. The project will run alongside the proposed TRIBUTE study which aims to see whether this treatment works for patients.

His MRC project will look at ways to improve the treatment and see whether the therapy may be used beyond Crohn’s disease.

Dr Irving said: “I am delighted to have been awarded this grant. This new scheme will enable research-active NHS clinicians to devote more time to research. I am also hugely grateful to my academic partner Professor Graham Lord, who is hosting me in his laboratory as well as to Professor Giovanni Lombardi and Professor Mike Malim for their support.”

Dr Daniel Lumsden is a Consultant in Paediatric Neurology and Complex Motor Disorders. His project will investigate a new type of imaging, to see if it could improve how doctors treat children with dystonia using deep brain stimulation. Dystonia is a painful disabling condition, causing uncontrollable muscle contractions. Most cases are in children who have cerebral palsy.

Dr Daniel Lumsden

He will work with children who have cerebral palsy and are receiving deep brain stimulation to treat their dystonia. He will use the latest imaging techniques, which King’s Health Partners can uniquely offer to children with movement problems like dystonia, to explore how deep brain stimulation influences the function of the brain, and whether this is an improvement over current imaging techniques.


Dr Lumsden said: “The funding provided by the MRC CARP will provide me with an invaluable opportunity to embed cutting edge research techniques into our clinical service, improving our understanding of how Deep Brain Stimulation works to improve uncontrolled movements and how we can best apply the intervention to improve the lives of the children and families we care for.”