Head of Bioinformatics

Translational Bioinformatics

Emanuele holds a PhD in biochemistry and has gained extensive knowledge in bioinformatics and cancer research through research activities carried out in biotech and pharmaceutical, as well as academic organizations. He has taken part and directed the development of open source and commercial software for the analysis of protein structures, microarray data, pathways and DNA polymorphisms and contributed to a number of cancer drug discovery programs. After several years in industry (LION Bioscience, Merck MRL) he joined the Breakthrough Breast Cancer Research Unit at King’s College London in 2009, where he worked with his team on the genomics/bioinformatics analysis of basal-like breast cancer and the identification of novel candidate targets and predictive biomarkers.

In 2013 he moved to the NIHR Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust and King’s College London, as the Head of the Bioinformatics Platform. With his team, Emanuele is involved in several translational programs spanning different therapeutic areas

His main topics of research are:

  • Cancer bioinformatics, genomics, molecular profiling, molecular biomarkers
  • Immune-phenotyping and analysis of mass cytometry (CyTOF) data
  • Genomic and clinical data integration
  • New target, diagnostic and biomarker discovery through integrative mining of large-scale molecular and clinical data
  • Development of novel methods for data analysis 

Contact

emanuele.de_rinaldis@kcl.ac.uk