The Good Manufacturing Practice (GMP) Unit is a flexible space to make cell and gene therapies for clinical trials.
It enables researchers to explore the growing field of Advanced Therapy Medicinal Products (ATMPs), which has heralded a new era in patient care and treatment in recent years.
ATMPs are increasingly being used to treat major indications that were previously unmet. As with all medicines, however, their safety and efficacy must be determined through clinical trials.
The GMP Unit ensures these trials can advance as smoothly and efficiently as possible. It is strategically placed within Guy’s Hospital to undertake the manufacturing requirements of ATMP clinical trials in collaboration with King’s College London and commercial companies.
We have particular expertise in closed-system cell cultures and purification.
Current examples of our work include the manufacture of patient-specific ATMPs for clinical trials in head and neck cancers and recipients of liver and kidney transplants.
The GMP Unit consists of three equipped clean-rooms designed to accommodate multiple production processes. They are small-scale and therefore perfect for early-phase trials.
The GMP Unit is open daily from 8am until 8pm for 48 weeks of the year and can be reserved using a hotel-style booking system. Each room has three four-hour sessions per day.