Date/Time
Date(s) - 24/10/2019
9:00 am - 12:30 pm

Location
NIHR Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust and King’s College London
16th Floor, Tower Wing, Guy’s Hospital, Great Maze Pond


This is an introductory / intermediate course for anyone who has exposure to logistic regression. This includes researchers who may wish to use logistic regression and clinicians who read the medical literature and want to gain a better insight into how results are reported. Use of specific statistical packages will not be covered.

Course description

Multivariable analyses are now ubiquitous within the medical literature, with logistic regression being one of the comMondayest techniques. Logistic regression quantifies the association between several independent variables (e.g. cholesterol, smoking, exercise, and hypertension) and a single, dichotomous outcome (e.g. heart disease).

The growth of statistical packages over the last decade has meant that clinicians can now perform this type of analysis without actually understanding its appropriate usage and limitations, leading potentially to erroneous conclusions.

This course will consider elements of logistic regression at both basic and intermediate levels, and covers:

  • Uses of logistic regression and types of model
  • The concept of odds ratio, how this differs from relative risk
  • Choice of scale for independent variables (e.g. categorical vs. continuous)
  • Variable selection procedures (which variables are in the final model and why?)
  • Interactions
  • Model diagnostics, goodness of fit, discrimination, calibration
  • Potential problems: over fitting, shrinkage, multicollinearity
  • How to report and interpret the final model.

Learning objectives

By the end of the session, students should be able to:

  • Understand potential applications and limitations of logistic regression
  • Interpret results within medical journals
  • Identify analyses that may have significant limitations.

NB: This course will not provide a comprehensive guide to model formulation.

NB: Use of specific statistical packages (e.g. SPSS) will NOT be covered.

Who can attend?

The courses are free for health care professionals employed by organisations associated with the National Institute of Health Research Biomedical Research Centre at Guy’s & St Thomas’ and King’s College London:

  • King’s College London
  • Guy’s and St Thomas’ NHS Foundation Trust
  • South London and the Maudsley NHS Foundation Trust
  • King’s College Hospital NHS Foundation Trust
  • St George’s University of London
  • St George’s Hospitals NHS Foundation Trust

Places are booked on a first come, first served basis. If the module is full, your name will be placed on a waiting list and if a place becomes available you will contacted at the latest 72 hours beforehand.

Non Attendance Policy

The courses in this programme are very popular and are often oversubscribed. If you are unable to attend a course you are booked on to you must notify us 72 hours in advance so we can offer the place to someone else.

If you do not attend on the day and are unable to provide a satisfactory explanation you may be removed from future course bookings.

For further information please contact the NIHR Guy’s and St Thomas’ BRC Research Training Programme at BRCTraining@gstt.nhs.uk.

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