2017 BRC PhD Programme

We are seeking to appoint  outstanding science graduates to a 4 Year or 1+3 PhD Studentship Programme partnered with KCL who will engage in internationally-competitive research projects. There is a choice to complete year one of the programme consisting of a rotation through three project areas and will include formal development of core and generic research skills. This will be followed by 3 years on a chosen PhD project. Alternatively students may enter directly into a 4-year PhD project with compulsory modules.
Candidates must possess, or be expected to achieve, a 1st or good upper 2nd class degree in a relevant subject and must meet KCL eligibility criteria
This fellowship is open to EU and Home students only.

This call is now closed

The full list of available projects can be found below.  Informal enquiries about PhD projects should be addressed to the designated project supervisor.

Supervisor Project Title Theme/s Cluster

Fiona M. Watt

The role of fibroblast subtypes in human disease

Cutaneous Medicine

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Professor Maddy Parsons

Receptor signalling mechanisms driving lung tumour cell growth

Cross cutting themes

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Ciro Chiappini

Nanoinjection gene therapy to treat skin blistering

Cutaneous Medicine

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Professor James McDonnell

Elucidating the molecular mechanisms of peanut allergies

Immunity & Infection

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Tamir Rashid

Engineering human gut-on-a-chip from patient specific induced pluripotent stem cells

Regenerative Medicine And Celluar Therapy

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Professor Peter Jones

Improving the outcomes of human islet transplantation as a therapy for Type 1 diabetes

Transplantation

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Dr Katie Doores

Broadly neutralizing antibodies in HIV infection

Immunity & Infection

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Dr Sophie Moore

Maternal health, breast milk bioactives and infant growth.

Women’s and Child Health

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Dr Grzegorz Woszczek

Mast cells in food allergy

Immunity & Infection

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Professor Anne Ridley

Functions of RhoA mutants in HTLV-1-induced adult T-cell leukaemia/lymphoma

Immunity & Infection

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Professor Khuloud Al-Jamal

Developing nanomedicines for immunosuppression in liver transplantation

Transplantation

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Dr Sophia N Karagiannis

Impact of glycosylation on tumour antigen-specific IgE antibody functions

Cutaneous Medicine

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Dr Afshan Malik

The role of mitochondrial DNA mutations and inflammation in adult blindness caused by diabetic retinopathy

Genomic Medicine

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Sophie Papa

SF-25 specific Chimeric Antigen Receptor T-cell development for melanoma

Cutaneous Medicine

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Antony D Gee

Radiolabelling, evaluation and validation of a new 18F metomidate for PET aldosteroma-mediated hypertension.

Cardiovascular disease

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Professor Hannah Gould

Understanding and Intervening in Atopic Diseases

Cutaneous Medicine

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Claire Wells

Developing live imaging 3D models of pancreatic cancer invasion to aid drug discovery

Imaging Sciences

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Mr Tim Jackson

Investigating the therapeutic potential of targeting collectin-11 as a treatment for age-related macular degeneration

Immunity & Infection

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Martyn Cobourne

Odontomas as prognostic markers for disrupted WNT signalling

Oral health

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Valeria Mondelli

Immunophenotypes in obesity: testing the role of inflammation in predicting weight loss and onset of depression after bariatric surgery

Immunity & Infection

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Eileen Gentleman

Hydrogels with cell-activated cytokine release for craniofacial bone regeneration

Regenerative Medicine And Celluar Therapy

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Dr. Gavin Bewick

Exploring the gut immunoendocrine axis in the pathogenesis of Inflammatory Bowel Disease.

Immunity & Infection

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Dr Maisa Seppala

Screening and functional analysis of candidate disease genes for ectodermal dysplasia

Oral health

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Pierre Guermonprez

Functional genomics of human dendritic cells: a stem cell based approach.

Immunity & Infection

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Jordana Bell

Exploring epigenetic alterations to elucidate the role of smoking in inflammatory bowel disease: implications for therapy

Genomic Medicine

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Claire Thornton

Manipulating mitophagy to provide neuroprotection after neonatal hypoxic-ischaemic brain injury

Women’s & Childrens health

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Axel Behrens

Mechanisms and biological function of c-Jun multisite phosphorylation in cancer

Immunity & Infection

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Professor JK Cruickshank

Unravelling arterial stiffening and hypertension using targetted plasma and urinary steroid-profiling metabolomics.

Cardiovascular disease

Cluster 1 – Advanced Therapeutics and Experimental Medicine

Mahvash Tavassoli

Mechanism of action of a cancer-selective toxin

Genomic Medicine

Cluster 1 – Advanced Therapeutics and Experimental
Medicine

Michael Malim

HIV-1 mediated reprogramming of T cell gene expression networks

Genomic Medicine

Cluster 2 – Precision Medicine

Professor Hannah Gould

Antibodies against Staphylococcal aureus enterotoxins (SAEs)

Cutaneous Medicine

Cluster 2 – Precision Medicine

Catherine Williamson

Impact of maternal cholestasis and dyslipidaemia on offspring susceptibility to diabesity and role of therapeutic agents in metabolic protection.

Genomic Medicine

Cluster 2 – Precision Medicine

Francesca Capon

A study of IL-36/IL-1 signalling as a new therapeutic target in palmar plantar pustulosis (PPP)

Cutaneous Medicine

Cluster 2 – Precision Medicine

Leonie Taams

Bridging cancer immunotherapy and inflammation biology

Immunity & Infection

Cluster 2 – Precision Medicine

Professor Mary Rutherford

Fetal brain development in gestational diabetes.

Imaging Sciences

Cluster 2 – Precision Medicine

Professor Cathryn Lewis

Towards personalised medicine for hypertension

Cardiovascular disease

Cluster 2 – Precision Medicine

Professor Juan Martin-Serrano

Novel roles of membrane remodelling genes in genome stability and the pathogenesis of cancer

Genomic Medicine

Cluster 2 – Precision Medicine

Monica Agromayor

Characterisation of novel candidate genes for kidney disease and their mechanism of pathogenesis

Genomic Medicine

Cluster 2 – Precision Medicine

Dr Rachel M Tribe

Understanding host defence peptide interactions with the vaginal microbiome in pregnancies at high risk of spontaneous preterm birth

Women’s & Childrens health

Cluster 2 – Precision Medicine

Mieke Van Hemelrijck

Impact of a cancer diagnosis on diabetes management and outcomes

Cardiovascular disease

Cluster 3 – Data Analytics

Francesca Ciccarelli

Identification of molecular biomarkers of multiple colorectal cancer through omic profiles.

Genomic Medicine

Cluster 3 – Data Analytics

Professor Christopher McKevitt

Knowledge translation, data integration, and patient involvement. A case study of the South London Stroke Registry as a provider of data for personalised medicine.

Cardiovascular disease

Cluster 3 – Data Analytics