2016 BRC Clinical Training Fellow

Applications for this call are closed 

This call for Clinical Training Fellowships (CTFs) is one of several training programmes funded by the BRC and overseen by the BRC Training Cluster STEM.  Specifically, we seek to appoint up to five trainees to undertake one year of protected research training in areas closely aligned to BRC focussed research clusters and their themes.  It is anticipated that during the period of the CTF successful candidates will be expected to 1) complete core training modules in Translational and Experimental Medicine, 2) actively pursue their research project and 3) prepare a research fellowship application for submission to an external funding body, such as a Research Council, Charity or NIHR to support further training towards a PhD during the tenure of the Fellowship.

The scheme is open to clinical trainees from across the UK who have had, until now, a significant clinical and training commitment that has not allowed them the protected time to develop their research careers.  Candidates should have:

  • Relevant professional qualification or degree with distinction/honours
  • Registration with relevant professional body
  • Eligibility and experience at a level appropriate for registering for a higher degree (eg MRes and PhD)

In addition candidates should demonstrate a track record of publications in peer-reviewed journals, in addition to educational achievement and a commitment to an academic career.  This fellowship is open to EU and Home students only.

The Job reference is 196-MED1052.  You can see full job advert on health jobs uk.

The full list of available projects can be found below.  Informal enquiries about CTF projects should be addressed to the designated project supervisor.

Supervisor Project Title Theme/s Cluster

Prof Ajay Shah, Prof Phil Chowienczyk Dr Nicholas Gall

Role of neuronal nitric oxide synthase in human orthostatic syndromes (PDF 36kb)

Cardiovascular

Cluster 1 – Experimental Medicine & Therapeutics

Dr Joerg Steier and Dr Gerrard F Rafferty

The feasibility of non-invasive electrical stimulation of the dilator muscles of the upper airway for the treatment of obstructive sleep apnoea. (PDF 66kb)

Environment, Respiratory Health and Allergy

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Professor Sven Plein, Dr Amedeo Chiribiri, Professor Paul Marsden

A direct comparison of CMR and PET perfusion using novel perfusion techniques and unique hybrid PET-MR scanner (PDF 261kb)

Cardiovascular Medicine/ Imaging and Biomedical Engineering

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Jane Howard, Professor Graham Lord

The control of obesity and type 2 diabetes by the adaptive immune system (PDF 34kb)

Infection and Immunity

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Professor Lucilla Poston, Dr Kate Bramham

The glycocalyx in pre-eclampsia: a potential therapeutic target? (PDF 35kb)

Cardiovascular Medicine

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Mr Bijan Modarai, Professor Alberto Smith

An investigation into the mechanisms that govern spinal cord ischaemia after endovascular repair of thoraco-abdominal aortic aneurysms (PDF 84kb)

Cardiovascular Medicine Imaging and Biomedical Engineering

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Francesca Capon & Prof Catherine Smith

An integrated analysis of IL-36 cytokines as biomarkers of skin autoinflammation (PDF 40kb)

Cutaneous Medicine, Translational Genetics

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Tanya Shaw, Mr Alastair Mackenzie Ross

Developmental basis of skin diversity

diversity Cutaneous Medicine

Cluster 1 – Experimental Medicine & Therapeutics

Dr Michael Robson and Prof Claudia Kemper

The effect of anti-neutrophil cytoplasmic antibodies on monocytes (PDF 29kb)

Transplantation

Cluster 1 – Experimental Medicine & Therapeutics

Prof Frank O Nestle, Prof Tim Spector

Dissecting the gene-environment interplay in allergic disorders by multi-omic analysis in monozygotic and dizygotic twins (PDF 36kb)

Translational genetics (Twins biomarker programme) Cutaneous medicine

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr James Galloway, Dr Sam Norton and Prof Andrew Cope

Signatures of clinical remission in patients with rheumatoid arthritis (40kb)

Immunity and Infection

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Mark O’Neill, Dr Sebastien Roujol and Prof Reza Razavi

The use of imaging guidance in the optimisation of VT substrate ablation (PDF 34kb)

Imaging and Biomedical Engineering,Cardiovascular Medicine

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Prof David Edwards, Prof Giovanni Montana

Genetic imaging to understand brain injury in preterm infants (PDF 59kb)

Imaging and Biomedical Engineering, Translational Genetics

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Caroline Jolley & Professor Steve Harridge

Understanding healthy ageing: neural respiratory drive as a physiological marker of ageing in the healthy respiratory system (PDF 389kb)

Environment, Respiratory Health & Allergy

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Stephen Till, Dr Grzegorz Woszczek,Dr Clive Grattan

Mechanism of Omalizumab (anti-IgE) in treatment of Chronic Spontaneous Urticaria (PDF 129 kb)

Cutaneous Medicine

Cluster 1 – Experimental Medicine & Therapeutics

Dr Steven Williams, Dr Steven Niederer and Professor Mark O’Neill

Pathophysiological Mechanisms of AF Associated with Atrial Septal Defects in Adults PDF 42kb)

Imaging and Biomedical Engineering

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Natalie Prescott, Dr Jeremy Sanderson and Professor Chris Mathew

Presymptomatic detection of intestinal inflammation in relatives of patients with Crohn’s disease (PDF 37kb)

Translational Genetics, Infection and Immunology

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Prof Jo Spencer and Dr Jeremy Sanderson

Development of the human marginal zone B cell response to bacterial polysaccharide antigens. (PDF 35kb)

Immunity and Infection

Cluster 1 – Experimental Medicine & Therapeutics

Professor Rinaldi and Dr Steven Niederer

The role of scar location and orientation in the response to cardiac resynchronisation therapy in ischemic cardiomyopathy patients. (35kb)

Imaging and Biomedical Engineering

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Tamir Rashid & Dr Fiona Wardle

Understanding transcriptional network regulation during human hepatic progenitor maturation to advance stem cell derived 3-D liver engineering (PDF 941kb)

Transplantation/ Experimental medicine & therapeutics/ Regenerative medicine

Cluster 1 – Experimental Medicine & Therapeutics

Professor Mark O’Neill, Professor Reza Razavi, Dr James Harrison, Professor Tobias Schaeffter

Catheter ablation of atrial fibrillation: intraprocedural cardiac magnetic resonance imaging (PDF 54kb)

Imaging & Biomedical Engineering

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Prof Phil Chowienczyk Prof Rene Botnar

Assessment of sodium and fluid homeostasis as a stratifier and biomarker in the treatment of hypertension and heart failure (PDF 29kb)

Cardiovascular imaging and biomarkers

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Prof Simon Redwood, Dr Jack Lee

Investigating the haemodynamic and physiological principles underlying low flow-low gradient aortic stenosis versus normal flow-high gradient aortic stenosis. (PDF 32kb)

Cardiovascular

Cluster 1 – Experimental Medicine & Therapeutics

Professor Aldo Rinaldi

Body surface mapping and invasive hemodynamic measurement to assess the optimal left ventricular pacing site. (PDF 70kb)

Atherosclerotic Disease

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Maria Hernandez Fuentes, Dr Marlies Ostermann

Inflammatory changes and identification of novel biomarkers in acute kidney injury (76kb)

Transplantation

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Pasupathy, Professor Lucilla Poston,Professor Debbie Lawlor

Improved characterisation of fetal growth anomalies associated with childhood obesity and metabolic syndrome – a life-course epidemiological study. (36kb)

Cardiovascular

Professor Alberto Smith ,Mr Prakash Saha

An investigation into the mechanisms that lead to in-stent thrombosis following deep venous reconstruction. (48 kb)

Cardiovascular Medicine, Imaging and Biomedical Engineering

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Frank McCaughan, Dr Paul Lavender

Early molecular pathogenesis of squamous lung cancer – intersection of inflammation and carcinogenesis (37kb)

Cancer

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Dr Nick Powell, Professor Claudia Kemper, Dr Ben Afzali

Defining novel pathways of mucosal T-cell activation in Inflammatory bowel disease (46kb)

Immunity and infection

Cluster 1 – Experimental Medicine & Therapeutics

Dr Ragai Mitry, Professor Anil Dhawan, Dr Emer Fitzpatrick

Cryopreservation of encapsulated hepatocyte alginate microbeads for treatment of acute liver failure (37kb)

Transplantation

Cluster 1 – Experimental Medicine & Therapeutics

Dr Andrew Webb, Dr Divaka Perera

Coronary and Forearm Macrovascular and Microvascular Responses to Inorganic Nitrite in Patients with Diabetes (81kb)

Cardiovascular

Cluster 1 – Experimental Medicine & Therapeutics

Dr Divaka Perera, Dr Andrew Webb, Dr Amedeo Chiribiri

Coronary and systemic vascular responses to exercise and pharmacological vasodilators in patients with angina due to microvascular dysfunction

Cardiovascular Medicine (cross-cutting with Imaging and Biomedical Engineering

Cluster 2 – Biomarkers, Co-diagnostics & Imaging

Clinical Research Training Fellowships

Professor Andrew Cope speaks to BRC clinical training fellows Lucy Durham and Natasha Hezelgrave about the one year fellowship.